CREATINE AND CREATININE IN WHOLE BLOOD AND PLASMA

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Creatine and Creatinine in Whole Blood and Plasma

The methods elaborated by Folk’ for the determination of small quantities of creatine and creatinine have been of great service in quantitative investigations involving these compounds, and the numerous criticisms and modifications suggested as improvements on the original technique are sufficient, evidence of their widespread use. But recent discussions2s 3, 4 have disclosed several possible s...

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Creatine and creatinine metabolism.

The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the enzymes and metabolites involved, and of the inherent implications for physiology and human pathology. Very recently, a series of new discoveries ...

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The first review of the literature on creatine and creatinine after the advent of the Folin colorimetric method was presented by Professor Mendel22 before a joint meeting of the Section on Physiology and Experimental Medicine of the American Association for the Advancement of Science and the biochemical, physiological and bacteriological societies in Baltimore in 1908. Although only four years ...

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Urea, creatinine, and glucose determined in plasma and whole blood by a differential pH technique.

We report the conditions (buffer composition and enzyme activity) required for estimating three frequently determined analytes--urea, glucose, and creatinine--by use of an improved version of the differential pH apparatus previously described (Clin Chem 29: 80-85, 1983). For each analyte, we used only one specific enzyme, thus avoiding a chain of auxiliary and indicator reactions. The method re...

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Elevated plasma creatinine due to creatine ethyl ester use.

Creatine is a nutritional supplement widely used in sport, physical fitness training and bodybuilding. It is claimed to enhance performance. We describe a case in which serum creatinine is elevated due to the use of creatine ethyl esther. One week after withdrawal, the plasma creatinine had normalised. There are two types of creatine products available: creatine ethyl esther (CEE) and creatine ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1917

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)86768-0